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Copper(II) Sulfate Anhydrous: An In-Depth Commentary

Historical Development

Long before laboratories started fine-tuning modern chemical compounds, copper(II) sulfate took its place in daily life under different names. Back in ancient times, smiths and miners recognized a blue stone, which eventually earned the title “blue vitriol.” After centuries of mining and accidental discoveries, alchemists in the 18th and 19th centuries dug deeper, isolating the anhydrous form through heating and crystallization. Farmers trusted it to control fungus on grapes in the Bordeaux region, with old journals listing recipes calling for “vitriol” drenched vines, establishing its roots in agriculture. Over time, academic curiosity about the element’s behavior gave rise to more refined versions, and the fine white powder of anhydrous copper(II) sulfate found its way into chemistry classrooms, water treatment plants, and power generation plants spanning continents.

Product Overview

Copper(II) sulfate anhydrous stands as a staple in labs and industries. Often found as a pale gray or white powder, the anhydrous form holds a reputation for being more chemically active than its blue, hydrated cousins. Traders, school teachers, and seasoned chemists recognize the distinction. This chemical appears as solid lumps or powder, with a biting metallic aftertaste when unwisely handled without gloves. Manufacturers label this compound under several product codes and trade names, reflecting specifications set by universities, pharmaceutical corporations, and electronics developers. Genuine users select their source based on purity and handling recommendations, knowing full well that impurities can wreck entire batches in sensitive work.

Physical & Chemical Properties

Diving into its character, copper(II) sulfate anhydrous carries the formula CuSO4. Unlike its hydrated cousin, this form lacks water molecules, so it appears off-white or gray, not blue. The powder weighs in at about 159.61 grams per mole, dense and gritty to the touch. Heat it, and it keeps its structure up to about 650°C, after which it breaks down. It doesn’t dissolve all that quickly unless given a stir or a slit of acid to speed things along. What stands out in daily practice—drop a speck in water, and a bright blue color surges out as it converts to the pentahydrate. It’s highly hygroscopic, sucking up moisture from the air, which often turns stored powder lumpy and blue if the cap gets left loose.

Technical Specifications & Labeling

Labels on copper(II) sulfate anhydrous containers aren’t for show. Responsible suppliers print batch numbers, purity percentages (typically ranging from 98% to 99.5%), and any sign of contaminants, especially iron or chlorides. Packing guidelines follow stringent standards—usually double-bagged, with tamper-proof caps. For strict lab or pharmaceutical work, analysts look for certified analytical grade or technical grade distinctions, checking certificates for trace metals or heavy minerals that might skew results. In my own experience, labs will reject shipments with even fractional deviations, since low-level impurities matter more in advanced electronics or drug synthesis than someone mixing fertilizer in the field.

Preparation Method

Solid, reliable methods for getting anhydrous copper(II) sulfate go back generations. Commercial-scale producers usually start with copper metal or oxides, dissolving them in sulfuric acid. Once fully dissolved, they heat the resulting blue pentahydrate crystals to about 150°C. This step drives off the water, leaving behind a chalky, pale solid. I spent enough hours in undergraduate labs timing this heat treatment, watching for the twitch from blue to gray. Mishandling the temperature, and you’re left with a crusty mess, full of burnt residue or half-reacted crystals. Industrial kits automate this with drum ovens and moisture analyzers, producing large runs in a fraction of the time it takes by hand.

Chemical Reactions & Modifications

Copper(II) sulfate anhydrous flashes its true value in reactions. Hydration turns it vivid blue, so it often lands in chemical test kits for water presence. In the lab, toss it into a reaction with zinc, and witness metallic copper spawn out, a vivid red-brown deposit forming inside the beaker. Students everywhere use it to study displacement series, or as a catalyst in organic syntheses, where it teams up with other acids and bases. Advanced researchers tweak it further—attaching other anions or cations, building specialty salts for materials science, or blending with carbonates and nitrates for electronics and specialty pigment production.

Synonyms & Product Names

Names for copper(II) sulfate anhydrous include cupric sulfate, blue vitriol (for hydrated form), roman vitriol, and simply “anhydrous copper sulfate” in everyday catalogues. Marketing departments often push their own codes—CUSO4, cuprum sulfuricum, or specific pharmaceutical trade names. These all trace back to the same family, the only difference lying in water content and fine-tuned purity.

Safety & Operational Standards

Day-to-day use of copper(II) sulfate anhydrous should focus on safety, owing to the risks it poses. Contact with skin causes irritation, and inhaling dust stirs up coughing fits or respiratory trouble. Storage demands sealed containers, kept away from acids or combustible materials to avoid corrosive leaks. Government and workplace standards go further, demanding personal protective equipment—goggles, nitrile gloves, and, if dust gets airborne, respirators. These aren’t overreactions; copper spills burn skin and, when dumped without care, pollute groundwater. I remember a case where a chemistry teacher ignored glove rules and wound up with blue fingerprints for days, further underscoring how even small lapses in handling can linger beyond the laboratory walls.

Application Area

No chemical sits on a shelf for looks alone, and copper(II) sulfate anhydrous proves its worth across industries. Farmers dose apple and grape orchards to keep fungus at bay, using the anhydrous powder as a base for mixing broad-spectrum fungicides. Municipal water plants deploy it to control algae bloom, dosing reservoirs to keep intake pumps clear. In mining, it finds a place in ore beneficiation, separating metals from waste during flotation. Electroplating shops employ it to give metals like iron and steel a resilient copper surface, boosting longevity and resistance to corrosion. I’ve watched art restoration teams use carefully sourced copper sulfate to remove tarnish or bring luster back to aging bronze works, balancing chemistry and beauty with every application.

Research & Development

Modern labs continue to unravel copper(II) sulfate anhydrous’s potential, delving into nanoscale materials and improved medical diagnostics. Scientists investigate how copper compounds might disrupt microbial biofilms, probing the roots of hospital-acquired infections. Research groups, especially those focusing on renewable energy, explore copper(II) salts as electrolytes in redox flow batteries, promising affordable energy storage for green power grids. Nanotechnology outfits grind it into ultra-fine particles, tweaking conductivity, magnetic field responses, or drug delivery behaviors. Collaboration between universities and tech firms keeps pushing the boundaries, with published studies in analytical chemistry journals describing ever sharper uses and increased efficiencies.

Toxicity Research

Efforts to understand copper(II) sulfate anhydrous’s toxicity stretch back decades, tracing its impact on people, wildlife, and entire ecosystems. Swallowing even a small amount leads to nausea and gastric distress, and higher exposures can damage kidneys and liver or bring on dangerous neurological symptoms. Livestock poisoning cases fill agriculture bulletins each year, too often from mismeasured veterinary doses or accidental blending in feed. Research teams set exposure limits and document effects, tracking bioaccumulation through waterways and crop systems. From my own interactions with toxicologists, I learned copper doesn’t break down readily, which means chronic exposure matters just as much as single events. Regulatory bodies set occupational exposure limits and demand strict reporting of spills or improper disposal to stop harm before it starts.

Future Prospects

Looking ahead, the world’s demand for high-performance chemicals continues its upward climb, and copper(II) sulfate anhydrous stays on the frontlines. Electric vehicle production draws on copper for its conductivity and resilience, giving rise to new demand for high-purity chemical feedstocks. Aquaculture industries keep seeking copper-based interventions as climate change shifts microbial landscapes and water chemistry. Meanwhile, green chemistry enthusiasts look to recycle spent copper compounds from old electronics and industrial processes, squeezing new value from substances once tossed as waste. I’ve sat in on working groups for tech startups where researchers brainstorm how to use anhydrous copper salts in next-generation battery cathodes, aiming for lower costs and faster recharge cycles. As regulatory pressure on pollution tightens, attention also turns toward sustainable synthesis methods, closing the loop to cut emissions and protect communities near production hubs.



What are the main uses of Copper (II) Sulfate Anhydrous?

The Role in Agriculture

Copper (II) sulfate anhydrous shows up often on farms and in greenhouses. Plant health can struggle when crops don’t pull enough copper from the soil. I’ve seen fruit trees and vegetables perk up once copper-based fertilizers get added in the right measure. The anhydrous form dissolves fast, which lets growers mix it precisely with water for foliar sprays. This compound helps fight certain fungal diseases—think downy mildew or blight—which, left unchecked, wipes out entire harvests. The reality is, good food production relies on more than just water and sunlight. A balanced input of micro-nutrients, copper included, means fewer sick plants and less wasted effort for the farmer.

A Chemistry Tool in Schools and Labs

Anyone who’s taken a basic chemistry class remembers the striking blue solution that copper sulfate creates in water. Teachers lean on it to reveal chemical reactions, test for water presence, or demonstrate crystals forming as water evaporates. The anhydrous type matters for experiments that need precision. If moisture sneaks in, the results turn muddy. Scientists appreciate its reliability as a drying agent, since the anhydrous grade jumps at the chance to absorb water, giving visual signals during qualitative analysis when testing for moisture in gases. In my experience, reliable lab results often hinge on controlling little things, and a good stash of copper (II) sulfate anhydrous has always helped keep the experiments trustworthy.

Industrial Processes and Electroplating

Factory work turns to copper (II) sulfate for its ability to lay down copper layers during electroplating. Plating drives many industries, from electronics to decorative goods. Think about printed circuit boards and those shining finishes on hardware—neither gets done without the right copper solution. The anhydrous version allows tighter control over metal content in the electrolyte bath, which means cleaner, tougher finishes at the end of the process. Factories need to deliver products that last, and plating adds both appearance and resistance to wear.

Public Health and Water Treatment

Keeping drinking water safe sometimes takes a little chemistry. Municipal water systems that use open reservoirs often battle algae blooms, favored by warm weather and fertilizer run-off. Even a small dose of copper sulfate can knock down that growth, keeping pipes clean and water flowing freely. The dose matters—a touch too much can risk harming fish or upsetting the ecosystem balance. So, water managers test and retest before adding anything to public water. Reliable chemical sources, such as copper (II) sulfate anhydrous, help them work with accuracy and safety, letting people trust the water coming out of their taps.

Looking Ahead: Managing the Risks

Every useful material comes with trade-offs. Copper toxicity can threaten aquatic life and soil health when over-applied. Farmers, scientists, and public works teams need clear guidelines and careful measurements. Better application equipment, updated training, and more frequent testing cut down on the bigger risks. New research focuses on alternatives and smarter delivery systems to put copper exactly where it’s needed, reducing waste and environmental impact. Making use of copper (II) sulfate anhydrous responsibly serves both industry and community needs—striking that balance is the real challenge and opportunity.

Is Copper (II) Sulfate Anhydrous hazardous or toxic?

What Copper (II) Sulfate Anhydrous Brings Into Everyday Life

Copper (II) sulfate anhydrous stands out as a staple in many labs, gardens, and schools. Its vibrant blue color in hydrated form, and plain white in the anhydrous state, hints at an interesting chemical character. The substance shows up on chemistry benches, crop fields, even as a treatment to clear ponds of algae. Plenty of folks pick it up thinking of science experiments, fertilizer blends, or pest control. But that sense of utility hides a rougher edge not everyone sees.

Toxic Effects: Straight Talk

The safety labels on copper sulfate bottles don’t just fill space. This compound can hurt people and animals. Ingesting a small dose causes nausea, vomiting, and abdominal pain before a person makes it to the hospital. A slightly larger exposure pushes the risk higher—potential for kidney and liver damage sits on the horizon. Breathing dust or fumes can trigger irritation in the nose, throat, or lungs, especially for those working around it day after day. I learned this the hard way back in grade school, watching a friend’s clumsy spill force us out while the science teacher scrambled for help.

Fish and aquatic critters handle copper sulfate anhydrous even worse. It acts as a biocide, which helps pond owners kill algae, but it also wipes out sensitive species in even smaller doses. That same property puts livestock and pets at risk if this chemical gets into water or pasture lands.

Why This Matters: Oversight and Common Sense

Many countries treat copper sulfate anhydrous as a hazardous substance for a reason. Handling instructions look strict for workers and commercial users. They wear gloves, eye protection, and keep emergency showers nearby. Parents, teachers, and gardeners often overlook these protocols, not out of laziness, but because these products appear on hardware store shelves with little fanfare. A chemical doesn't need to be explosive or a strong acid to do real harm. Small exposures add up over time.

In my experience, those warning labels seem easy to ignore until a close call happens. Cases pop up during school science projects or garden mixing mishaps, leading to calls to poison control or even emergency rooms. Safety data from the Centers for Disease Control and Prevention (CDC) spells it out: copper sulfate ranks as both a health and environmental hazard. Its toxicity exceeds that of many fertilizers and household cleaners.

Paths Toward Safer Handling and Better Community Awareness

Education brings change. Training for hobbies and professional use makes a difference, but it starts with clear messages on packaging and in classrooms. Kids and adults need reminders to store it out of reach, avoid skin contact, and use it outdoors or in well-ventilated areas. Simple habits—wearing gloves, using goggles, washing up—lower risk right away.

Communities can push for better guidance from retailers and public agencies. Local hazardous waste collection programs offer responsible ways to get rid of old or unused supplies, so the runoff doesn't reach waterways or wildlife. Teaching respect for potentially dangerous chemistry prepares everyone for safer, smarter choices whether in a backyard, classroom, or farm field.

Key Facts to Remember

Copper (II) sulfate anhydrous supports important roles in science and agriculture, but its hazards are no secret to those who read up. The risks to health and ecosystems deserve close attention. Safer handling, proper disposal, and better information make a lasting difference in how this classic chemical serves the community, not just industry.

How should Copper (II) Sulfate Anhydrous be stored?

Easy to Overlook, Essential to Get Right

Copper (II) sulfate anhydrous doesn’t demand much attention until things go wrong. Left out, this blue white salt drinks up water from the air fast. Pile a few mistakes together, and pretty much overnight you've got a useless, clumpy mess. Chemistry classes and industrial labs both rely on it for everything from fungicide blending to school science demos. What may seem like a harmless powder can get dangerous or wasteful if someone leaves it open on a crowded workbench.

Why Air and Water Spell Trouble

Most folks who spent time in science labs remember copper sulfate because it stains oddly or turns deep blue from even a few drops of water. That means water vapor in the air isn't just an annoyance — it changes the chemical itself, turning it into a hydrated form and hurting the accuracy of any measurements or experiments. If you work with exact recipes, accuracy is gone as soon as that open jar hits humid air.

Mixing the wrong form into fertilizers, animal feed, or experiments without checking leads to errors, unplanned chemical reactions or, worse, disposal headaches. The more humid your storage area, the faster the shift happens. Years working in southern labs showed me nothing clumps faster than improperly capped chemical jars during a rainy week. Even away from the coast, poorly sealed bags become blue bricks before lunch.

Containment Over Convenience

The correct way to store copper (II) sulfate anhydrous comes down to two words: airtight sealing. Don't use plastic bags or cheap containers. Heavy-duty glass bottles with solid plastic or rubber-lined screw caps stop most environmental moisture. Industry supply catalogs now sell thick plastic tubs with gasket lids for bigger batches. Multiple layers of containment, like keeping the bulk supply in a sealed drum and refilling small bottles for daily use, cuts down on open-air exposure.

Drying agents, or desiccant packs, add a shield against stray humidity. I’ve seen places tuck silica gel canisters inside cabinets—an extra guard rail for rainy climates or buildings with poor ventilation. Keep those packs dry by switching them out every few months, especially after long storage or unpredictable weather shifts.

Think Location, Not Just Containers

Even the best cap means little if the storeroom itself feels muggy eight months a year. Walk through most science stockrooms or chemical sheds, you’ll see climate makes or breaks safety and shelf life. A small air conditioner or dehumidifier changes the game, especially during summer. It’s not about luxury—it’s practicality. Cooler and drier mean fewer ruined supplies and less hazardous cleanup.

One overlooked trick is to separate incompatible chemicals. Copper sulfate doesn’t mix well with strong acids and organic solvents. Always give it its own spot, away from splash dangers and far from direct sunlight that might heat the contents or warp cheap containers.

Routine, Not Just Rules

Habit makes good storage work. Check containers for cracks or sticky lids. Top off desiccant packs and avoid leaving the chemical out during busy work. Print labels with the date opened and hydration status. These simple routines save money and cut risks, whether in a high school supply closet or a huge warehouse.

Smart Storage Pays Off

Safe, dry copper sulfate lasts longer and avoids headaches. Whether you’ve seen too many ruined batches or simply want smooth lab work, putting in the effort to protect this chemical pays off every single day.

What is the chemical formula and appearance of Copper (II) Sulfate Anhydrous?

Understanding Copper (II) Sulfate Anhydrous

Copper (II) sulfate anhydrous carries the chemical formula CuSO4. This simple arrangement of copper, sulfur, and oxygen comes up often in laboratories and industry. Unlike its blue hydrated form, the anhydrous version looks quite different, so it’s easy for anyone with background in chemistry—even at a high school level—to spot the difference just by eye.

Appearance and Key Properties

Take CuSO4 anhydrous out of its container and you’ll see a grayish white to pale green powder or granules. No vivid blues here—that’s strictly for the pentahydrate. This change happens because the anhydrous form has lost its water molecules, which give the pentahydrate its splashy blue color. It reminds me of watching water evaporate off sidewalks after a summer storm; something plain gets left behind, signaling that a change has happened even if the chemical building blocks remain the same.

The dry form soaks up water from the air, which means it’s a hygroscopic material. Leave it out and it’ll soon pick up moisture, gradually shifting color as it transforms into the blue pentahydrate. This isn’t just trivia—scientists and technicians have relied on this color-change reaction for ages as a quick check for the presence of water in various substances. In practice, CuSO4 anhydrous sits in desiccators, working as a reliable water-sniffer, alerting us at a glance if something’s gotten wet.

Why Knowing the Difference Matters

Understanding physical and chemical distinctions between copper (II) sulfate anhydrous and its hydrated sibling affects fields ranging from chemistry labs to large-scale manufacturing. Accidentally mistaking the two can throw off measurements, ruin experiments, and lead to unpredictable results. Back in my college days, a simple mix-up in the lab meant redoing a whole afternoon’s work—turns out, anhydrous copper (II) sulfate absorbs water like a sponge, shifting weights and concentrations in ways that mess with calculations.

Teachers underscore these differences to help students spot potential pitfalls. For industrial users, mislabeling anhydrous and hydrated forms could lead to expensive mistakes. Think about pharmaceutical manufacturing or agriculture. The wrong ingredient doesn’t just mean wasted time—it might spark safety problems or environmental risks. Data from various chemical safety boards has shown that simple mix-ups between chemical forms have led to bulk product recalls and even environmental contamination events. For example, the Environmental Protection Agency has documented several cases where improper storage or labeling of copper compounds resulted in accidental waterway runoff, spurring costly cleanup efforts.

Encouraging Better Practices

Promoting clear education on chemical properties and regularly reinforcing best practices should remain top priorities for anyone working with potentially hazardous materials. Proper labeling and thorough training slash error rates. Safety data sheets give straightforward details on appearance, hazards, storage, and emergency action, helping users tell at a glance which copper compound they’re dealing with.

Fundamentals—like distinguishing between grayish powder and bright blue crystals—may seem basic, but that knowledge saves time and money. For anyone working in a lab or supervising chemical stocks, paying attention to something as simple as the form of copper sulfate they have on hand isn’t just smart—it’s essential. Prevention beats clean-up every time, and strong knowledge underpins safe, reliable chemical use.

Can Copper (II) Sulfate Anhydrous be used in agriculture or as a pesticide?

Digging into an Old-School Farm Tool

Copper (II) sulfate anhydrous goes back generations on the farm. Folks still remember their grandparents calling it “blue stone.” In fields and greenhouses, copper sulfate’s story ties to a fight with fungal blights and stubborn algae. Anyone who has tended crops or kept an eye on orchards has likely seen that familiar blue powder in spray tanks.

Fungicide and Beyond

Blight, mildew, and black spot threaten both yield and the bottom line for growers. Copper sulfate steps in with proven results, especially for fruits like grapes and apples. Its main job: disrupt fungal cells, halt spore growth, and keep diseases from spreading. Several studies back this up, including long-term trials from the University of California showing good outcomes against downy mildew.

In my own time working with small vineyards, copper sprays kept mildew under control where organic approaches with sulfur alone didn’t cut it. The visible change on leaves after a week always impressed me. Yet, experience also teaches that too much copper does more harm than good. Overapplication leads to stunted plants and tough soil conditions.

Dealing with Pests and Algae

Copper sulfate can pull double duty as an algaecide, handling scummy irrigation ditches and livestock ponds. It starves out algae populations by blocking vital enzyme reactions, keeping water clearer for crops and animals alike. Some folks also use it for slug and snail control in gardens. Results in the field often depend on right timing and doses—too high and fish in that pond take the brunt.

The trickier part comes with insect pests. Most insects dodge copper's toxic effects unless it’s mixed in a broader pest-control program. Traditional growers lean heavier on it as an anti-fungal than as a multi-purpose pesticide, and most agricultural extension agents will echo that sentiment.

Sustainability, Safety, and Smarter Use

Copper doesn’t break down in the soil. Over years, copper builds up, turning healthy ground into a harsh zone for earthworms and friendly microbes. In my area, old orchards can’t be re-planted right away due to legacy copper buildup. That stuff sticks around, so the question isn’t just “Does it work?” but “How do we avoid harm?” France and several EU countries already set strict limits on annual copper use per hectare, nudged by research on soil health decline.

On the safety front, I once handled some without gloves and learned the lesson—the irritation faded, but the memory stuck. Masks and good boots protect more than regulations demand. For those working with large tanks, having washing stations steps away can mean the difference in a mishap.

Where Do We Go From Here?

Copper sulfate’s long history gives it a sturdy place in farming. Lower rates and rotation with other products slow down potential soil problems. Some integrated pest management plans let growers cut copper applications by half, swapping in biocontrols or disease-resistant plant varieties. Extension offices and crop consultants continue to experiment, because permanent solutions require creative thinking.

No silver bullet replaces copper overnight, yet plenty of growers push for greater care each year. Using record books, soil tests, and scheduled rotations, agriculture can keep old tools alive while protecting fields for the next round of planting.

Copper (II) Sulfate Anhydrous
Copper (II) Sulfate Anhydrous
Names
Preferred IUPAC name Copper(II) sulfate
Other names Copper sulfate
Cupric sulfate
Blue vitriol (when hydrated)
Bluestone (when hydrated)
Cupric sulphate
Copper(2+) sulfate
Pronunciation /ˈkɒp.ər tuː ˈsʌl.feɪt ænˈhaɪ.drəs/
Identifiers
CAS Number 7758-98-7
Beilstein Reference 1722993
ChEBI CHEBI:23414
ChEMBL CHEMBL1201180
ChemSpider 14058
DrugBank DB09153
ECHA InfoCard 03b1b557-537b-4910-ab91-98283f4f8b43
EC Number 231-847-6
Gmelin Reference 778
KEGG C00621
MeSH D003550
PubChem CID 24083
RTECS number GL8900000
UNII 45O3Q8V2V9
UN number UN3077
Properties
Chemical formula CuSO4
Molar mass 159.61 g/mol
Appearance White to grayish-white powder
Odor Odorless
Density 3.6 g/cm³
Solubility in water 23.1 g/100 mL (20 °C)
log P -2.3
Vapor pressure Negligible
Acidity (pKa) -2.0 (H2O)
Basicity (pKb) 6.37
Magnetic susceptibility (χ) +72.0×10⁻⁶ cm³/mol
Refractive index (nD) 1.673
Dipole moment 0 D
Thermochemistry
Std molar entropy (S⦵298) 109.5 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -771.4 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -769.1 kJ/mol
Pharmacology
ATC code A12CX04
Hazards
Main hazards Harmful if swallowed, causes serious eye irritation, may cause respiratory irritation, toxic to aquatic life with long lasting effects.
GHS labelling GHS02, GHS07, GHS09
Pictograms GHS06,GHS09
Signal word Danger
Hazard statements H302, H315, H319, H410
Precautionary statements P264, P270, P273, P280, P301+P312, P305+P351+P338, P330, P337+P313, P370+P378, P501
Lethal dose or concentration LD50 Oral Rat 300 mg/kg
LD50 (median dose) LD50 (median dose): Oral-rat LD50: 300 mg/kg
NIOSH WN5600000
PEL (Permissible) PEL (Permissible Exposure Limit) for Copper (II) Sulfate Anhydrous: "1 mg/m³ (as Copper dust and mists, OSHA PEL)
REL (Recommended) REL: 1 mg/m³
Related compounds
Related compounds Copper (II) sulfate pentahydrate
Copper (II) chloride
Copper (II) nitrate
Cupric oxide
Copper (I) sulfate
Copper (II) carbonate